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Clinical trials for glioblastoma
Glioblastoma is an area of intense research, and trials range from new drugs to devices and vaccines. Study sites are listed on each record, and for a study open at only a few centers, travel is often the deciding factor, so it is worth checking where each one is running.
322 recruiting trials. Showing a sample.
- recruitingEARLY_Phase 1NCT06072586
A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
This study will administer the investigational drug, BDTX-1535 to eligible patients with recurrent high-grade glioma (HGG) and newly-diagnosed glioblastoma (nGBM). BDTX-1535 was designed to block a growth signal important to some cancers. BDTX-1535 is being tested in this stud...
Listed by the study for Glioblastoma. Record updated 2025-11-20.
Sponsored by St. Joseph's Hospital and Medical Center, PhoenixFull details on ClinicalTrials.gov → - recruitingNANCT06090903
Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma
This clinical trial uses a type of imaging scan called magnetic resonance imaging (MRI) to study brain tumor biology in patients with glioblastoma that can be removed by surgery (resectable). Malignant gliomas are the second leading cause of cancer mortality in people under th...
Listed by the study for Glioblastoma. Record updated 2025-11-10.
Sponsored by Jonsson Comprehensive Cancer CenterFull details on ClinicalTrials.gov → - recruitingEARLY_Phase 1NCT07284069
Senicapoc and Perampanel for Newly Diagnosed Glioblastoma
Glioblastoma is the most common and aggressive form of brain cancer in adults. Despite surgery, radiotherapy, and chemotherapy, most patients only live about one year after diagnosis. There is an urgent need for new and better treatments. Recent research has shown that gliobl...
Listed by the study for Glioblastoma. Record updated 2026-05-07.
Sponsored by Aarhus University HospitalFull details on ClinicalTrials.gov → - recruitingNCT05839379
Targeted Pediatric High-Grade Glioma Therapy
The goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma. This molecular profiling will decide if patients are eligible to participate in a subsequent tre...
Listed by the study for Glioblastoma. Record updated 2026-09-08.
Sponsored by Nationwide Children's HospitalFull details on ClinicalTrials.gov → - recruitingPhase 1NCT05366179
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
The purpose of this study is to test the safety of using T lymphocyte chimeric antigen receptor cells against the B7-H3 antigen (CAR.B7-H3T cells) in patients with glioblastoma. CAR.B7-H3T cells treatment has not been tested in humans and is not an approved treatment by the Fo...
Listed by the study for Glioblastoma Multiforme. Record updated 2026-04-22.
Sponsored by UNC Lineberger Comprehensive Cancer CenterFull details on ClinicalTrials.gov → - recruitingPhase 3NCT06556563
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
This is a multicenter, two-arm, randomized, double-blind, placebo-controlled study of Optune® (Tumor Treating Fields at 200 kHz) together with maintenance Temozolomide (TMZ) chemotherapy agent and pembrolizumab compared to Optune® together with maintenance TMZ and placebo in n...
Listed by the study for Glioblastoma. Record updated 2026-08-19.
Sponsored by NovoCure GmbHFull details on ClinicalTrials.gov → - recruitingNANCT07552233
NK Cell Therapy for Malignant Solid Brain Tumors
This is a multi-center, open-label investigator-initiated trial (IIT) designed to evaluate the safety, tolerability, and feasibility of combined intracranial and intravenous administration of ex vivo expanded and activated natural killer (NK) cells in adult patients with malig...
Listed by the study for Glioblastoma (GBM). Record updated 2026-04-27.
Sponsored by Peking University Third HospitalFull details on ClinicalTrials.gov → - recruitingPhase 1, Phase 2NCT07093814
A Study of VRT106 for Injection in Patients With Recurrent/Progressive Glioblastoma
This study is an open-label, single-arm Phase I/II clinical trial with the primary objective of evaluating the safety, tolerability, and efficacy of VRT106 in patients with recurrent/progressive glioblastoma.
Listed by the study for Glioblastoma. Record updated 2026-01-02.
Sponsored by Guangzhou Virotech Pharmaceutical Co., Ltd.Full details on ClinicalTrials.gov → - recruitingPhase 2NCT05708352
A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment
This is a Phase 2, randomized two-armed, multi-site study of 170 patients with newly diagnosed glioblastoma multiforme. Patients will be randomized 1:1 to receive Keto Diet, or Standard Anti-Cancer Diet. All patients will receive standard of care treatment for their glioblasto...
Listed by the study for Glioblastoma Multiforme. Record updated 2026-08-05.
Sponsored by Cedars-Sinai Medical CenterFull details on ClinicalTrials.gov → - recruitingPhase 1NCT05353530
IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma
This is a phase I study to assess the safety and feasibility of IL-8 receptor modified patient-derived activated CD70 CAR T cell therapy in CD70+ adult glioblastoma
Listed by the study for Glioblastoma Multiforme. Record updated 2026-05-27.
Sponsored by University of FloridaFull details on ClinicalTrials.gov →
Data from ClinicalTrials.gov, retrieved 2026-09-16. Study sponsors write and update their own records there, including the recruitment status shown here, and the U.S. government does not review or approve every study listed. A trial showing up here is not a recommendation and not a determination that anyone qualifies. Eligibility is decided by the trial's own doctors.
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Add whatever you know: an age, a city, a mutation from a pathology report. We'll narrow the list to trials that fit. Describe it in your own words.
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Common questions
- Is this glioblastoma trial finder really free?
- Yes. You describe the situation, we search ClinicalTrials.gov and show what matches. No account, no payment, no email required. Nothing you type is saved.
- Does showing up here mean the patient qualifies?
- No. A listing here is not a recommendation, and the U.S. government does not review or approve every study on ClinicalTrials.gov. These are trials worth asking your care team about. Every trial has detailed eligibility criteria that the trial's own doctors evaluate, and many depend on test results and treatment history that only your medical team knows in full.
- How current is this list?
- The trials come directly from ClinicalTrials.gov and are refreshed daily, with the retrieval date shown under the list. Each study record is written and kept up to date by that study's own sponsor, so the recruitment status is what the sponsor last reported. Each result links to the full, live record, and the finder above always runs a fresh search when you use it.
- What should I do with a trial that looks promising?
- Bring it to your oncologist or care team, and mention the NCT number (the ID that starts with NCT). They can tell you whether it is a genuine fit and refer you to the trial site.
Found trials worth discussing? Keep them next to the records.
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