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Clinical trials for multiple myeloma
Multiple myeloma has a deep bench of trials, including CAR-T and bispecific antibodies. Which trials fit usually depends on how many prior treatments there have been.
560 recruiting trials. Showing a sample.
- recruitingPhase 2NCT06762769
Isatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering Myeloma
The study will test a new combination of 3 drugs: Isatuximab (Isa), Iberdomide (Iber) and Dexamethasone (Dex), in patients who have intermediate or high risk smouldering myeloma. Smouldering myeloma is an early form of myeloma which may progress to active multiple myeloma, but...
Listed by the study for Smouldering Myeloma. Record updated 2025-08-01.
Sponsored by University College, LondonFull details on ClinicalTrials.gov → - recruitingPhase 3NCT03562169
The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)
Study design: Randomised, controlled, multi-centre, open-label, phase III trial (with a single intervention registration phase). Primary Objectives The primary objectives of this study are to determine: * The impact on Depth of Response (DoR: less than VGPR versus VGPR or b...
Listed by the study for Multiple Myeloma. Record updated 2018-06-19.
Sponsored by University of LeedsFull details on ClinicalTrials.gov → - recruitingPhase 2NCT05847569
Alternate Doses and Dosing Schedules of Belantamab Mafodotin for Treatment of Triple-Class Refractory Multiple Myeloma
This phase II trial tests alternate doses and dosing schedules of belantamab mafodotin in treating patients with triple-class multiple myeloma that has come back (after a period of improvement) (recurrent) and/or does not respond to treatment (or that has not responded to prev...
Listed by the study for Recurrent Multiple Myeloma. Record updated 2026-07-14.
Sponsored by Mayo ClinicFull details on ClinicalTrials.gov → - recruitingPhase 2NCT07509086
IL-15-Armored CAR-T Therapy in Relapsed or Refractory Multiple Myeloma and Plasma Cell Leukemia
This is an open-label, single-arm, Phase 2 study to evaluate the efficacy and safety of IL-15-armored chimeric antigen receptor T-cell (CAR-T) therapy in subjects with relapsed or refractory multiple myeloma and plasma cell leukemia.
Listed by the study for Relapsed/Refractory Multiple Myeloma. Record updated 2026-04-03.
Sponsored by The First Hospital of Jilin UniversityFull details on ClinicalTrials.gov → - recruitingPhase 1, Phase 2NCT05850234
AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)
This trial is a Phase 1b/2, open-label, multicenter study of AZD0120, a CD19/BCMA dual CAR T-cell therapy, in adult subjects with relapsed/refractory multiple myeloma.
Listed by the study for Relapsed/Refractory Multiple Myeloma. Record updated 2026-08-17.
Sponsored by AstraZenecaFull details on ClinicalTrials.gov → - recruitingPhase 1, Phase 2NCT04271644
BCMA-Targeted CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma and Plasma Cell Disease
This is a single arm study to evaluate the efficacy and safety of BCMA-targeted CAR-T cells therapy for patients with relapsed/refractory Multiple Myeloma.
Listed by the study for Multiple Myeloma. Record updated 2025-02-25.
Sponsored by Chongqing Precision Biotech Co., LtdFull details on ClinicalTrials.gov → - recruitingPhase 1, Phase 2NCT05828511
A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment
This study is researching an experimental drug called linvoseltamab (called "study drug"). The study is focused on participants with newly diagnosed multiple myeloma (NDMM) who are eligible for high dose chemotherapy with autologous stem cell transplantation (transplant-eligib...
Listed by the study for Multiple Myeloma. Record updated 2026-05-13.
Sponsored by Regeneron PharmaceuticalsFull details on ClinicalTrials.gov → - recruitingPhase 3NCT07582432
A Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex in Participants With Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma
The main goal of this study is to show that people with certain immune problems (from Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma) get fewer serious infections when they receive Gamunex C through an IV once every 4 weeks, along with their usual medi...
Listed by the study for Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma. Record updated 2026-05-12.
Sponsored by Grifols Biologicals, LLCFull details on ClinicalTrials.gov → - recruitingPhase 1NCT07558915
A Study to Evaluate RO7851624 in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
This study will evaluate safety, pharmacokinetics (PK), clinical activity and pharmacodynamics (PD) of RO7851624 in participants with RRMM who are triple-class exposed (treated with proteasome inhibitors \[PIs\], immunomodulators \[IMiDs\], and anti-cluster of differentiation ...
Listed by the study for Relapsed/Refractory Multiple Myeloma. Record updated 2026-09-14.
Sponsored by Genentech, Inc.Full details on ClinicalTrials.gov → - recruitingPhase 2NCT05091372
Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma
To increase the conversion rate from MRD-positive to MRD-negative CR in patients with newly diagnosed multiple myeloma (NDMM) receiving post-transplant maintenance therapy with belantamab mafodotin plus lenalidomide.
Listed by the study for Myeloma Multiple. Record updated 2026-08-14.
Sponsored by M.D. Anderson Cancer CenterFull details on ClinicalTrials.gov →
Data from ClinicalTrials.gov, retrieved 2026-09-16. Study sponsors write and update their own records there, including the recruitment status shown here, and the U.S. government does not review or approve every study listed. A trial showing up here is not a recommendation and not a determination that anyone qualifies. Eligibility is decided by the trial's own doctors.
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Common questions
- Is this multiple myeloma trial finder really free?
- Yes. You describe the situation, we search ClinicalTrials.gov and show what matches. No account, no payment, no email required. Nothing you type is saved.
- Does showing up here mean the patient qualifies?
- No. A listing here is not a recommendation, and the U.S. government does not review or approve every study on ClinicalTrials.gov. These are trials worth asking your care team about. Every trial has detailed eligibility criteria that the trial's own doctors evaluate, and many depend on test results and treatment history that only your medical team knows in full.
- How current is this list?
- The trials come directly from ClinicalTrials.gov and are refreshed daily, with the retrieval date shown under the list. Each study record is written and kept up to date by that study's own sponsor, so the recruitment status is what the sponsor last reported. Each result links to the full, live record, and the finder above always runs a fresh search when you use it.
- What should I do with a trial that looks promising?
- Bring it to your oncologist or care team, and mention the NCT number (the ID that starts with NCT). They can tell you whether it is a genuine fit and refer you to the trial site.
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