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Clinical trials for sarcoma

Sarcoma is a family of rare cancers with many distinct subtypes, and trials are usually subtype-specific. Naming the exact sarcoma type is the single most useful detail.

564 recruiting trials. Showing a sample.

  • recruitingPhase 2NCT05333458

    Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial

    This phase II trial tests whether atezolizumab in combination with selinexor works to shrink tumors in patients with alveolar soft part sarcoma and whether the study drugs are better than the usual approach in treating this type of cancer. The usual approach is defined as care...

    Listed by the study for Advanced Alveolar Soft Part Sarcoma. Record updated 2026-08-14.

    Sponsored by National Cancer Institute (NCI)Full details on ClinicalTrials.gov →
  • recruitingPhase 1NCT06021626

    A Study of CRD3874-SI in People With Solid Tumors

    This study will test the safety of a study drug called CRD3874-SI. The researchers will test different doses of CRD3874-SI to find the highest dose that causes few or mild side effects in participants. After the researchers find the highest safe dose of CRD3874-SI, they will t...

    Listed by the study for Sarcoma. Record updated 2026-08-13.

    Sponsored by Memorial Sloan Kettering Cancer CenterFull details on ClinicalTrials.gov →
  • recruitingNCT05653388

    Metastatic Leiomyosarcoma Biomarker Protocol

    Leiomyosarcoma (LMS) is one of the most prevalent soft tissue sarcomas (STS) and can occur in various sites including soft tissue, uterus and retroperitoneal large vessels. Metastatic disease occurs in approximately 50% of patients diagnosed with leiomyosarcoma and prognosis i...

    Listed by the study for Leiomyosarcoma. Record updated 2026-06-24.

    Sponsored by University of Michigan Rogel Cancer CenterFull details on ClinicalTrials.gov →
  • recruitingNANCT07406087

    Navigation Intervention for Adolescent and Young Adult Cancer Survivors

    The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivor population; and 2) Plan and conduct an effectiveness-implementation trial of this program within Kaiser Permanente S...

    Listed by the study for Sarcoma. Record updated 2026-07-06.

    Sponsored by Kaiser PermanenteFull details on ClinicalTrials.gov →
  • recruitingNCT03099681

    An Observational Study on Epithelioid Sarcoma

    Prospective Italian study aimed to provide a description of the population affected by Epithelioid Sarcoma (ES)

    Listed by the study for Epithelioid Sarcoma. Record updated 2025-11-18.

    Sponsored by Italian Sarcoma GroupFull details on ClinicalTrials.gov →
  • recruitingPhase 2NCT06760819

    A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

    Researchers are looking for a better way to treat people who have solid tumors with HER2-activating mutations. Before a treatment can be approved for people to take, researchers do clinical trials to better understand its safety and how it works. In this trial, the researcher...

    Listed by the study for Sarcoma. Record updated 2026-09-03.

  • recruitingNCT04845893

    Observational Study on Skeletal Ewing's Sarcoma

    Observational prospective trial aimed to collect the collect demographic, clinical, surgical, pathological and molecular characteristics and treatment from patients affected by skeletal Ewing Sarcoma

    Listed by the study for Ewing Sarcoma of Bone. Record updated 2026-01-02.

    Sponsored by Italian Sarcoma GroupFull details on ClinicalTrials.gov →
  • recruitingNANCT06004011

    AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW)

    Adolescents and young adults living with HIV experience higher premature mortality from cancer than their uninfected peers. In Zambia, because of multilevel barriers, interventions for early diagnosis and optimized treatment to reduce this cancer mortality are underutilized fo...

    Listed by the study for Kaposi Sarcoma. Record updated 2026-01-15.

  • recruitingPhase 3NCT06422806

    Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

    This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differen...

    Listed by the study for Metastatic Dedifferentiated Liposarcoma. Record updated 2026-09-08.

    Sponsored by National Cancer Institute (NCI)Full details on ClinicalTrials.gov →
  • recruitingNANCT05751733

    Apatinib Mesylate Versus Standard Second-line TKI in the Treatment of Advanced GIST

    The goal of this Mesylate apatinib versus standard second-line TKI in the treatment of advanced gastrointestinal stromal tumors: a randomized, open, controlled, single-center clinical study is to explore the efficacy and safety of Apatinib compared with second-line treatment i...

    Listed by the study for Gastrointestinal Stromal Tumors. Record updated 2023-03-02.

    Sponsored by Xiangya Hospital of Central South UniversityFull details on ClinicalTrials.gov →

Data from ClinicalTrials.gov, retrieved 2026-09-16. Study sponsors write and update their own records there, including the recruitment status shown here, and the U.S. government does not review or approve every study listed. A trial showing up here is not a recommendation and not a determination that anyone qualifies. Eligibility is decided by the trial's own doctors.

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Add whatever you know: an age, a city, a mutation from a pathology report. We'll narrow the list to trials that fit. Describe it in your own words.

Whatever you have: the diagnosis, a mutation if you know it, age, where you live.

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Common questions

Is this sarcoma trial finder really free?
Yes. You describe the situation, we search ClinicalTrials.gov and show what matches. No account, no payment, no email required. Nothing you type is saved.
Does showing up here mean the patient qualifies?
No. A listing here is not a recommendation, and the U.S. government does not review or approve every study on ClinicalTrials.gov. These are trials worth asking your care team about. Every trial has detailed eligibility criteria that the trial's own doctors evaluate, and many depend on test results and treatment history that only your medical team knows in full.
How current is this list?
The trials come directly from ClinicalTrials.gov and are refreshed daily, with the retrieval date shown under the list. Each study record is written and kept up to date by that study's own sponsor, so the recruitment status is what the sponsor last reported. Each result links to the full, live record, and the finder above always runs a fresh search when you use it.
What should I do with a trial that looks promising?
Bring it to your oncologist or care team, and mention the NCT number (the ID that starts with NCT). They can tell you whether it is a genuine fit and refer you to the trial site.

Found trials worth discussing? Keep them next to the records.

The next step is a conversation with the care team, and that goes better when the scans, labs, and trial details live in one place everyone in the family can see. That's what KeptWell is: the binder, but it understands what's inside.

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