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Clinical trials for melanoma
Melanoma has been a proving ground for immunotherapy, and many trials build on that. Some are limited to tumors with a BRAF mutation, so that detail is worth including if you have it.
465 recruiting trials. Showing a sample.
- recruitingPhase 2NCT07310784
A Phase II Trial of LM103 in Advanced Melanoma
A total of 92 subjects with advanced melanoma who met the inclusion criteria will be randomly assigned in a 1:1 ratio to the experimental group and the control group in this phase II trial. The study will be followed up until 24 months after treatment.
Listed by the study for Advanced Melanoma. Record updated 2026-08-31.
Sponsored by Suzhou BlueHorse Therapeutics Co., Ltd.Full details on ClinicalTrials.gov → - recruitingNCT06887348
A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3
This is a noninterventional, observational, long-term follow-up (LTFU) study. Patients in this study will be followed for 5 years from enrollment on this study to assess potential delayed risks of RPx products. Eligible participants for this LTFU study include patients who rec...
Listed by the study for Melanoma. Record updated 2026-01-12.
Sponsored by Replimune, Inc.Full details on ClinicalTrials.gov → - recruitingPhase 4NCT07405086
Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study
This phase IV trial is evaluating whether morning versus afternoon administration of standard of care immunotherapy impacts its effectiveness in treating patients with solid tumors that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts...
Listed by the study for Advanced Melanoma. Record updated 2026-06-12.
Sponsored by OHSU Knight Cancer InstituteFull details on ClinicalTrials.gov → - recruitingNANCT07406087
Navigation Intervention for Adolescent and Young Adult Cancer Survivors
The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivor population; and 2) Plan and conduct an effectiveness-implementation trial of this program within Kaiser Permanente S...
Listed by the study for Melanoma (Skin Cancer). Record updated 2026-07-06.
Sponsored by Kaiser PermanenteFull details on ClinicalTrials.gov → - recruitingPhase 1NCT04903119
Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma
This is a phase 1 dose-escalation study of nilotinib in combination with fixed-dose dabrafenib and trametinib regimen for patients with metastatic or unresectable melanoma carrying a BRAF V600 mutation and have relapsed on a BRAF/MEK inhibitor therapy. The goal is to assess th...
Listed by the study for Metastatic Melanoma. Record updated 2026-02-13.
Sponsored by Rina PlattnerFull details on ClinicalTrials.gov → - recruitingPhase 1, Phase 2NCT04895709
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
The purpose of this study is to assess the safety, tolerability, and recommended dose(s) of BMS-986340 as monotherapy and in combination with nivolumab, docetaxel, or Pumitamig in participants with advanced solid tumors. This study is a first-in-human (FIH) study of BMS-986340...
Listed by the study for Melanoma. Record updated 2026-08-17.
Sponsored by Bristol-Myers SquibbFull details on ClinicalTrials.gov → - recruitingNANCT04693377
Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial
This trial compares cryoablation combined with stereotactic body radiation therapy to stereotactic body radiation therapy alone to see how well they work in treating patients with pain from cancer that has spread to the bones (bone metastases). Bone is a common site of metasta...
Listed by the study for Metastatic Melanoma. Record updated 2026-04-15.
Sponsored by M.D. Anderson Cancer CenterFull details on ClinicalTrials.gov → - recruitingNANCT04424719
Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME)
Biomarkers search for early diagnosis of liver metastases in patients with uveal melanoma who benefit from a follow-up tailored to their personalized risk of relapse.
Listed by the study for Uveal Melanoma. Record updated 2025-09-03.
Sponsored by Institut CurieFull details on ClinicalTrials.gov → - recruitingPhase 3NCT05522660
Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer
The primary objective of the study is to assess the efficacy in terms of CNS-specific PFS of the combination of standard systemic treatment plus SRS vs. standard systemic treatment alone in patients with newly diagnosed and untreated (except for surgery) asymptomatic or oligos...
Listed by the study for Melanoma. Record updated 2026-04-27.
Sponsored by ETOP IBCSG Partners FoundationFull details on ClinicalTrials.gov → - recruitingPhase 2NCT06121180
Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma
The goal of this clinical research study is to find out if Cemiplimab plus Ziv-Aflibercept is safe and effective in treating your condition of metastatic (spread to other parts of your body) uveal melanoma. This research study will test the study drugs to see if the combinatio...
Listed by the study for Metastatic Uveal Melanoma. Record updated 2025-12-04.
Sponsored by H. Lee Moffitt Cancer Center and Research InstituteFull details on ClinicalTrials.gov →
Data from ClinicalTrials.gov, retrieved 2026-09-16. Study sponsors write and update their own records there, including the recruitment status shown here, and the U.S. government does not review or approve every study listed. A trial showing up here is not a recommendation and not a determination that anyone qualifies. Eligibility is decided by the trial's own doctors.
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Add whatever you know: an age, a city, a mutation from a pathology report. We'll narrow the list to trials that fit. Describe it in your own words.
Trials for other conditions
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Common questions
- Is this melanoma trial finder really free?
- Yes. You describe the situation, we search ClinicalTrials.gov and show what matches. No account, no payment, no email required. Nothing you type is saved.
- Does showing up here mean the patient qualifies?
- No. A listing here is not a recommendation, and the U.S. government does not review or approve every study on ClinicalTrials.gov. These are trials worth asking your care team about. Every trial has detailed eligibility criteria that the trial's own doctors evaluate, and many depend on test results and treatment history that only your medical team knows in full.
- How current is this list?
- The trials come directly from ClinicalTrials.gov and are refreshed daily, with the retrieval date shown under the list. Each study record is written and kept up to date by that study's own sponsor, so the recruitment status is what the sponsor last reported. Each result links to the full, live record, and the finder above always runs a fresh search when you use it.
- What should I do with a trial that looks promising?
- Bring it to your oncologist or care team, and mention the NCT number (the ID that starts with NCT). They can tell you whether it is a genuine fit and refer you to the trial site.
Found trials worth discussing? Keep them next to the records.
The next step is a conversation with the care team, and that goes better when the scans, labs, and trial details live in one place everyone in the family can see. That's what KeptWell is: the binder, but it understands what's inside.
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